Enzyme: Pyruvate decarboxylase with at least two peer-reviewed articles.

And it should have at least one primary article from an American chemical society publication.

 What organism(s) utilize the biomolecule? Is it homologous to enzymes in other organisms?

 A discussion of the structure and function of the biomolecule.

 How does it catalyze the reaction? Acid-base catalysis? Cleavage of carbon-carbon bond? Oxidation? Something different? There are hundreds of reaction types; describe the reaction.

 What cofactors, if any, does it require?

 What are the substrates and end products?

 Are there any known inhibitors? If so, how do they inhibit the reaction?

 If a 3-D structure is known, include an image and discussion of the structure. ( image do not count toward the page requirements )

 What are the kinetic parameters? KM, kcat, specific activity, pH optimum, etc., and for what substrates?

 


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