Question 5
1 point possible (graded)
Which of the following would you expect to observe in the cells of insects poisoned with rotenone? (select two answers)
increased activity of the regulated enzymes of gluconeogenesis
increased activity of the regulated enzymes of glycolysis
increased lactate fermentation
increased O2 consumption
increased cellular ATP

Question 6
1 point possible (graded)
The catabolic pathways that degrade fatty acids do not generate ATP directly, but produce NADH and acetyl-CoA. Given what you know about cellular metabolism, which of the following enzymes is required to completely break down fatty acids?
acetyl-CoA carboxylase, which catalyzes the formation of malonyl-CoA from acetyl-CoA
pyruvate dehydrogenase, which catalyzes the formation of acetyl-CoA from pyruvate
fumarase, which catalyzes the conversion of fumarate to malate in the TCA cycle
lactate dehydrogenase, which catalyzes the fermentation of pyruvate into lactate

Question 7
1 point possible (graded)
What molecules in the list below can contribute to ATP synthesis in the absence of oxygen? (select two answers)
⦁ Palmitate (a 16-carbon fatty acid)
⦁ Acetyl-CoA
⦁ Glycogen
⦁ Glucose
⦁ NADH

Question 8
0.0/1.0 point (graded)
Suppose you have a patient who has been poisoned with either DNP or cyanide, but you do not know which. Recall that cyanide inhibits the oxidation of complex IV by oxygen, leading to an accumulation of reduced ETC components. By contrast, DNP disrupts the hydrogen ion gradient in mitochondria without interfering with the activity of the ETC.


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